Lefèvre Research Group

CNRS, Chimie ParisTech – Paris, France
Host institution : UMR 8060 i-CLeHS, Catalysis, Synthesis of Biomolecules and Sustainable Development Team (CSB2D)

Guillaume Lefèvre

I obtained my PhD in 2012 at the Ecole Normale Supérieure de Paris under the guidance of Dr. Anny Jutand, where I developed an expertise in molecular electrochemistry used as an investigation tool for mechanistic studies of transition-metal-calatyzed transformations. During this time, I worked in a close collaboration with the group of Pr. Carlo Adamo and Dr. Ilaria Ciofini (ENSCP ChimieParisTech, Paris), where I acquired skills in computational chemistry (DFT techniques applied to organometallic species). During a postdoctoral fellowship in the group of Prof. Peter Legzdins (University of British Columbia, Vancouver, Canada, 2012-2014; DOW Chemicals Fellowship), I worked in the field of C─H activation of saturated hydrocarbons involving tungsten nitrosyl complexes. I joined the Commissariat à l’Energie Atomique (CEA, group of Dr. Thibault Cantat) as a Chargé de Recherches (CNRS) in September 2014, focusing my research activity on two main axes : the development of new methodologies for the valorization of CO2 and its derivatives on one hand, and the development and mechanistic understanding of new low-valent iron-catalyzed coupling processes on the other hand.

In 2019, I moved back to Paris, in Chimie ParisTech, in the Catalysis, Synthesis of Biomolecules and Sustainable Development team (CSB2D, directed by Dr. Virginie Vidal) of the i-CLeHS institute. I keep developing new projects related to the reactivity of non-noble metals in catalysis, with a particular focus on low-valent iron chemistry and a strong interest in physical methods applied to the understanding of the mechanisms involved in those transformations.

Awards and fundings

  • 2021
    JSP Fellowship
    Swiss Chemical Society, e-Bürgenstock Conference
  • 2020-2025
    ERC Starting Grant – Project DoReMI
    (DOminating REdox Mechanisms in Iron-mediated C-C bond formations : reactivity, new paradigms and applications)
  • 2019-2023
    Scientific coordinator of the program “PheroCHEM”, involving the CNRS and the M2i Development company (synthesis of pheromones involving non-noble-metal-catalyzed key coupling steps).
  • 2019-2023
    French scientific coordinator of the International Research Program (IRP) IrMaCAR (Iron and Manganese-CAtalyzed Reactions).
    Partnership between the CNRS and the Ludwig Maximilians Universität (group of Pr. Paul Knochel, Munchen)
  • 2016-2020
    French National Research Agency – Project SIROCCO
    (Stable IROn catalysts for C-C Cross COupling, Young Researchers Program)
  • 2009-2012
    PhD fellowship, École Normale Supérieure de Cachan (FR)


Dr. Guillaume Lefèvre
CNRS, Chimie ParisTech
11 rue Pierre et Marie Curie
75231 Paris Cedex 5
Email : guillaume.lefevre@chimieparistech.psl.eu
Telephone : +33 1 85 78 41 70